Directing a drug to the exact tissue that needs it is one of the hardest problems in medicine. We're solving it by decoding the body's glycan code — the sugar-based signatures unique to every tissue. Through high-throughput in silico and in vivo screening, we map tissue glycan signatures at cellular resolution and design peptides that recognize them.
We're starting with the brain, the largest unmet need in medicine. Our lead peptide lets subcutaneously injected payloads — peptides, antibodies, mRNA, ASO, siRNA — cross the blood-brain barrier via transcytosis. We're a team of serial entrepreneurs in Cambridge, MA, sprinting toward the clinic.